皮膚の試験

Home > Preclinical dermatology studies

Rough skin models

  • Type of study
  • Animals
  • Notes

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Rough skin model

Hairless mice
Periods of rough skin preparation, treatment and measurement: Negotiable
Agents used for preparation of rough skin: Acetone, acetone/ether
Transepidermal water loss (TEWL) values will be compared.
Changes in transepidermal water loss (TEWL)

Photoaging wrinkle models

Model animals will be prepared by UVB irradiation.
Evaluation will be made by observation for wrinkles and by preparation of replica.

  • Type of study
  • Animals
  • Notes

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Photoaging wrinkle model

Hairless mice
UVB irradiation: 345 μW/cm2 for 2 min 54 sec
Observation for wrinkles: 3 times/week for 10 weeks
Treatment with the test substance: once/day for 8 weeks
Observation for wrinkles: once/week for 8 weeks
Darkening scores
セルミナディープホワイトジェル塗布時の色彩色差 L値の変化

育毛試験

Evaluation of new hair growth/hair restoration

  • Type of study
  • Animals
  • Notes

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Hair growth studies

C3H mice (number required: 10-12)
Evaluation based on the days and areas of new hair growth and the length and weight of hair.
媒体投与14日目 1%ミノキシジル投与14日目
  • 投与後の発毛日
  • 投与期間中の発毛指数(発毛面積)
  • 試験終了後の毛長
  • 試験終了後の毛重量

その他

The establishment of new studies is also available.
Please feel free to consult us regarding any type of study.

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