Food-related studies｜LIFE SCIENCE LABORATORIES,LTD.

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Life Science Laboratories, Ltd. conducts safety studies of functional food and food additives.
Efficacy studies of food are also available. These studies will be useful for your product development.

Type of study
Animals/bacterial strains/cells
Duration of the study

Single oral dose toxicity studies

5 mice or rats/sex

Approx. 1.5 months

Repeated oral dose toxicity studies
※Please consult us regarding the duration of the study and dose levels (number of groups).

5 mice or rats/sex/group

At least
3 months

Genotoxicity studies

Ames test (bacterial reverse mutation test)

5 bacterial strains

Approx.
1 month
Chromosomal aberration test

Cultured Chinese hamster cells

Approx.
3 months
Micronucleus test

≥ 5 mice or rats/sex/group

Approx.
2 months

Type of study
Animals/bacterial strains/cells
Duration of the study

Repeated oral dose toxicity studies(28 days, 90 days and 1 year)

≥ 5 mice or rats/sex/group

At least
3 months

Antigenicity studies (Maximization Test and Buehler Test)

≥ 5 guinea pigs/group

Approx.
2 months

Mutagenicity studies

Ames test（bacterial reverse mutation test）

5 bacterial strains

Approx.
1 month
Chromosomal aberration test

Cultured Chinese hamster cells

Approx.
3 months
Micronucleus test

Mice or rats

Approx.
2 months

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